Institute of Biochemical Engineering

Research and teaching in the fields of molecular biology, computational biology as well as bioprocess engineering and modelling

Welcome at our Institute

What is our focus?

Research at the Institute of Biochemical Engineering (IBVT) focuses on subcellular, cellular and intercellular studies to gain a quantitative understanding of underlying control and regulatory mechanisms in microbial and mammalian cells. Studies cover a broad range including RNA-RNA interactions, cell free protein synthesis, metabolic and transcriptional systems analysis and many more.

Results are used to enable knowledge-based strain and biochemical engineering from the lab to the production scale. Wet- and dry lab tools are developed to ease strain and process development. As such, experiments and modelling are intertwined thereby opening the door to the production of novel products using newly created strains with optimized chassis.

Novel production processes in cell-cell and cell-bioreactor (DFG InterZell) are the research focus of the DFG SPP ‘InterZell’, coordinated by Prof. Ralf Takors. Stay in touch with us on LinkedIn, Twitter and Instagram.

Accordingly, research at IBVT links conventional biochemical engineering approaches with the mindset of systems metabolic engineering and synthetic biology. Microbial cells such as Escherichia coliPseudomonas putidaCorynebacterium glutamicumClostridium ljungdahliiVibrio natriegens, yeasts such Saccharomyces cerevisiae, or mammalian cells such as Chinese hamster ovary are typically applied. IBVT offers fermentation capacities up to 300 L scale including downstream processing facilities. Profound metabolomics accompany bioprocess development.

IBVT is closely networked with multiple national and international research groups and companies and a member of the Stuttgart Research Center of Systems Biology, SRCSB.

Research activities at the Institute of Biochemical Engineering (IBVT) at the University of Stuttgart are in line with the majority of urgent fields of action identified by the United Nations (UN) in 2015. This applies in particular to

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